Journal article
Relationship between clinical macular changes and retinal function in age-related macular degeneration
PN Dimitrov, LD Robman, M Varsamidis, KZ Aung, G Makeyeva, L Busija, AJ Vingrys, RH Guymer
Investigative Ophthalmology and Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2012
DOI: 10.1167/iovs.11-8958
Abstract
PURPOSE. The aim of this study was to investigate the relationship between clinical macular changes and retinal function in age-related macular degeneration (AMD). METHODS. We recruited 357 participants with visual acuity of better than 20/60 in the study eye, including 64 individuals with normal fundi and 293 AMD participants classified into 12 subgroups based upon the International Classification and Grading System. Visual function in the study eye was assessed using two steady-state tests (achromatic 14 Hz flicker [F14Hz] and isoluminant blue color [BCT]) and two adaptation measurements (cone photo-stress recovery rate [CRR] and rod dark adaptation recovery rate [RRR]). The groups were co..
View full abstractRelated Projects (2)
Grants
Awarded by National Health and Medical Research Council (NHMRC) Project
Awarded by Australian Research Council Linkage Project
Funding Acknowledgements
Supported by grants from National Health and Medical Research Council (NHMRC) Project Grant 350224 (RHG, AJV), Australian Research Council Linkage Project (ARC-LP0211474), NHMRC CCRE, NHMRC practitioner fellowship (RHG), RVEEH Wagstaff Fellowship (LDR), RVEEH Research Committee and the Macular Vision Loss Support Society of Australia. Postdoctoral fellowship jointly funded by the Melbourne Centre for Epidemiology, Biostatistics, and Health Services Research and Centre for Research Excellence in Translational Neuroscience. CERA receives Operational Infrastructure Support from the Victorian Government.